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leprae. Anin silicostudy was carried out to be aware of the molecular interactions concerning DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 were revealed to own better inhibitory exercise againstM. lepraeDNA gyrase than Many others. On top of that, Evaluation using quinolone-resistantM. lepraeDNA gyrases showed that WQ-3334 experienced increased